How the Immune System Works. (Record no. 33045)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 05877nam a22004693i 4500 |
| 001 - CONTROL NUMBER | |
| control field | EBC7104327 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | MiAaPQ |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20240724115711.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS | |
| fixed length control field | m o d | |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr cnu|||||||| |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 240724s2015 xx o ||||0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781118997819 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 9781118997772 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (MiAaPQ)EBC7104327 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (Au-PeEL)EBL7104327 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)1347027465 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | MiAaPQ |
| Language of cataloging | eng |
| Description conventions | rda |
| -- | pn |
| Transcribing agency | MiAaPQ |
| Modifying agency | MiAaPQ |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | QR181 .S667 2016 |
| 082 0# - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616.07899999999995 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Sompayrac, Lauren M. |
| 245 10 - TITLE STATEMENT | |
| Title | How the Immune System Works. |
| 250 ## - EDITION STATEMENT | |
| Edition statement | 1st ed. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | Newark : |
| Name of producer, publisher, distributor, manufacturer | John Wiley & Sons, Incorporated, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2015. |
| 264 #4 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | ©2015. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource (291 pages) |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 490 1# - SERIES STATEMENT | |
| Series statement | New York Academy of Sciences Series |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Intro -- Dedication -- Title page -- Copyright -- Acknowledgments -- How to Use This Book -- LECTURE 1 An Overview -- INTRODUCTION -- PHYSICAL BARRIERS -- THE INNATE IMMUNE SYSTEM -- THE ADAPTIVE IMMUNE SYSTEM -- A COMPARISON OF THE INNATE AND ADAPTIVE IMMUNE SYSTEMS -- THE INNATE SYSTEM RULES! -- EPILOGUE -- LECTURE 2 The Innate Immune System -- INTRODUCTION -- THE COMPLEMENT SYSTEM -- THE PROFESSIONAL PHAGOCYTES -- HOW IMMUNE SYSTEM SENTINELS RECOGNIZE INVADERS -- HOW THE INNATE IMMUNE SYSTEM DEALS WITH VIRUSES -- THE INNATE IMMUNE SYSTEM - A COOPERATIVE EFFORT -- A PROPORTIONAL RESPONSE -- SUMMARY FIGURE -- LECTURE 3 B Cells and Antibodies -- INTRODUCTION -- THE B CELL RECEPTOR -- HOW THE BCR SIGNALS -- HOW B CELLS ARE ACTIVATED -- CLASS SWITCHING -- ANTIBODY CLASSES AND THEIR FUNCTIONS -- SOMATIC HYPERMUTATION -- B CELLS MAKE A CAREER CHOICE -- SUMMARY FIGURE -- LECTURE 4 The Magic of Antigen Presentation -- INTRODUCTION -- CLASS I MHC MOLECULES -- CLASS II MHC MOLECULES -- ANTIGEN PRESENTATION BY CLASS I MHC MOLECULES -- ANTIGEN PRESENTATION BY CLASS II MHC MOLECULES -- ANTIGEN PRESENTING CELLS -- THE LOGIC OF CLASS I MHC PRESENTATION -- THE LOGIC OF CLASS II MHC PRESENTATION -- CROSS-PRESENTATION -- NON-CLASSICAL MHC MOLECULES AND LIPID PRESENTATION -- MHC PROTEINS AND ORGAN TRANSPLANTS -- SUMMARY FIGURE -- LECTURE 5 T Cell Activation -- INTRODUCTION -- T CELL RECEPTORS -- HOW A T CELL'S RECEPTORS SIGNAL -- CD4 AND CD8 CO-RECEPTORS -- CO-STIMULATION -- A TIME-LAPSE PHOTO OF HELPER T CELL ACTIVATION -- HOW KILLER T CELLS ARE ACTIVATED -- FAIL-SAFE ACTIVATION -- LECTURE 6 T Cells at Work -- INTRODUCTION -- HELPER T CELLS AS CYTOKINE FACTORIES -- THE DENDRITIC CELL AS "COACH" OF THE IMMUNE SYSTEM TEAM -- Th1 HELPER T CELLS -- Th2 HELPER T CELLS -- Th17 HELPER T CELLS -- Th0 HELPER T CELLS -- LOCKING IN THE HELPER T CELL PROFILE. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | DELAYED-TYPE HYPERSENSITIVITY -- HOW CTLs KILL -- SUMMARY FIGURE -- LECTURE 7 Secondary Lymphoid Organs and Lymphocyte Trafficking -- INTRODUCTION -- LYMPHOID FOLLICLES -- HIGH ENDOTHELIAL VENULES -- LYMPH NODES -- PEYER'S PATCHES -- THE SPLEEN -- THE LOGIC OF SECONDARY LYMPHOID ORGANS -- LYMPHOCYTE TRAFFICKING -- WHY MOTHERS KISS THEIR BABIES -- LECTURE 8 Restraining the Immune System -- INTRODUCTION -- ATTENUATING THE IMMUNE RESPONSE -- DEACTIVATING THE SYSTEM -- LIFE IS SHORT -- EXHAUSTION -- LECTURE 9 Self Tolerance and MHC Restriction -- INTRODUCTION -- THE THYMUS -- MHC RESTRICTION -- THE LOGIC OF MHC RESTRICTION -- THYMIC TESTING FOR TOLERANCE OF SELF -- GRADUATION -- THE RIDDLE OF MHC RESTRICTION AND TOLERANCE INDUCTION -- TOLERANCE BY IGNORANCE -- TOLERANCE INDUCTION IN SECONDARY LYMPHOID ORGANS -- PERIPHERAL TOLERANCE INDUCTION -- TOLERANCE DUE TO ACTIVATION-INDUCED CELL DEATH -- B CELL TOLERANCE -- MAINTENANCE OF B CELL TOLERANCE IN GERMINAL CENTERS -- POSITIVE SELECTION OF NATURAL KILLER CELLS -- LECTURE 10 Immunological Memory -- INTRODUCTION -- INNATE MEMORY -- ADAPTIVE MEMORY -- PROPERTIES OF ADAPTIVE MEMORY CELLS -- COMPARING B AND T CELL MEMORIES -- INNATE VERSUS ADAPTIVE MEMORY -- LECTURE 11 The Intestinal Immune System -- INTRODUCTION -- INTESTINAL ARCHITECTURE -- HOW THE INTESTINAL IMMUNE SYSTEM DEALS WITH INVADERS -- HOW DOES THE INTESTINAL IMMUNE SYSTEM TELL FRIEND FROM FOE? -- LECTURE 12 Vaccines -- INTRODUCTION -- GENERATING MEMORY HELPER T AND B CELLS -- GENERATING MEMORY KILLER T CELLS -- STRATEGIES FOR VACCINE DEVELOPMENT -- VACCINE ADJUVANTS -- WILL THERE BE AN AIDS VACCINE? -- LECTURE 13 The Immune System Gone Wrong -- INTRODUCTION -- PATHOLOGICAL CONDITIONS CAUSED BY A NORMAL IMMUNE RESPONSE -- DISEASES CAUSED BY DEFECTS IN IMMUNE REGULATION -- AUTOIMMUNE DISEASE -- LECTURE 14 Immunodeficiency -- INTRODUCTION. |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | GENETIC DEFECTS LEADING TO IMMUNODEFICIENCY -- AIDS -- LECTURE 15 Cancer and the Immune System -- INTRODUCTION -- CANCER IS A CONTROL SYSTEM PROBLEM -- CLASSIFICATION OF CANCER CELLS -- IMMUNE SURVEILLANCE AGAINST CANCER -- IMMUNE SURVEILLANCE BY MACROPHAGES AND NK CELLS -- VACCINATION TO PREVENT VIRUS-ASSOCIATED CANCER -- Glossary -- List of Acronyms and Abbreviations -- Index -- EULA. |
| 588 ## - SOURCE OF DESCRIPTION NOTE | |
| Source of description note | Description based on publisher supplied metadata and other sources. |
| 590 ## - LOCAL NOTE (RLIN) | |
| Local note | Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Immune system-Effect of space flight on. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Immune system-Physiology. |
| 655 #4 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Print version: |
| Main entry heading | Sompayrac, Lauren M. |
| Title | How the Immune System Works |
| Place, publisher, and date of publication | Newark : John Wiley & Sons, Incorporated,c2015 |
| International Standard Book Number | 9781118997772 |
| 797 2# - LOCAL ADDED ENTRY--CORPORATE NAME (RLIN) | |
| Corporate name or jurisdiction name as entry element | ProQuest (Firm) |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | New York Academy of Sciences Series |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://ebookcentral.proquest.com/lib/orpp/detail.action?docID=7104327">https://ebookcentral.proquest.com/lib/orpp/detail.action?docID=7104327</a> |
| Public note | Click to View |
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