Epilepsy and Brain Tumors.
Newton, Herbert B.
Epilepsy and Brain Tumors. - 1st ed. - 1 online resource (292 pages)
Front Cover -- Epilepsy and Brain Tumors -- Copyright -- Dedication -- Contents -- Foreword -- Preface -- Contributors -- Chapter 1: Brain Tumor-Related Epilepsy: Introduction and Overview -- Introduction -- Epilepsy: Definition, Incidence, Social Context and Treatment Options -- Epilepsy in the Context of BTs: Epidemiology and Incidence -- Detection, Classification, and Documentation of Seizures -- The Unique Role of Epileptogenesis and Drug Resistance in BTRE -- Pharmacoresistance -- QoL in BTRE Patients -- Impact of AEDs in BTRE Patients -- Neurocognitive Evaluation and Possible Rehabilitative Programs -- Health Economics and BTRE -- References -- Chapter 2: Overview of Epidemiology, Pathology, and Treatment of Primary Brain Tumors -- Epidemiology of PBT -- Pathology of Selected PBT -- Diffuse Astrocytomas -- Localized Astrocytomas -- Oligodendrogliomas and Oligoastrocytomas -- Medulloblastoma and Other Embryonal Tumors -- Meningioma and Other Tumors of the Meninges -- Primary Central Nervous System Lymphoma -- Surgical Therapy of PBT -- Radiation Therapy of PBT -- Chemotherapy of PBT -- Molecular or ``Targeted´´ Treatment -- References -- Chapter 3: Overview of Epidemiology, Pathology, and Treatment of Metastatic Brain Tumors -- Epidemiology of MBTs -- Pathology of MBTs -- Surgical Therapy of MBTs -- Radiation Therapy of MBTs -- Chemotherapy of MBTs -- Acknowledgments -- References -- Chapter 4: Supportive Care of Brain Tumor Patients -- Introduction -- Seizures and Anticonvulsant Therapy -- Corticosteroids -- Gastric Acid Inhibitors -- Thromboembolic Complications and Anticoagulation -- Dysphagia and Swallowing Disorders -- Psychiatric Issues -- Pain Control Issues -- Palliative Care -- Ethical Issues -- Conclusion -- References -- Chapter 5: Brain-Tumor-Related Epilepsy in Children -- The Pediatric Perspective. Epilepsy-Associated Brain Tumors -- Pathophysiology -- Epidemiology -- Brain Tumors -- Seizures and Epilepsy -- Presentation -- Brain Tumors -- Seizures and Epilepsy -- General Principles of Management -- History and Physical Exam -- Diagnostic Evaluation -- Scalp EEG -- Intracranial EEG -- MRI -- Other Imaging Studies -- Magnetic and Electrical Source Localization -- Neuropsychological Assessment and Other Studies Used to Localize Eloquent Brain -- Genetics -- Tissue Diagnosis and Molecular Tumor Markers -- Medical Management -- Anticipatory Guidance -- Maintenance Antiseizure Drugs -- Rescue Antiseizure Drugs -- Role of Antiseizure Drugs in Children Without a History of Seizures -- Chemotherapy, Biologic Agents, and Steroids -- Dietary Considerations and Alternative Therapies -- Surgical Management -- Goals and Approaches -- Timing of Surgical Resection -- Lesionectomy (Tumorectomy) Versus Lesionectomy ``Plus´´ -- Palliative Strategies -- Outcome -- Future Directions -- References -- Chapter 6: Mechanisms of Focal Epileptogenesis -- Time Course and Specificity of Acquired Epileptogenesis -- References -- Chapter 7: Pathophysiology of Brain Tumor-Related Epilepsy -- Introduction -- Epidemiology of BTRE -- Pathophysiology of BTRE -- Treatment of BTRE -- References -- Chapter 8: The Neurophysiology of Central Nervous System Tumors -- Introduction -- EEG Modalities and Applications -- EEG Background Changes -- Epileptiform Activity -- Meningiomas -- Generation of Abnormal Cerebral Activity -- References -- Chapter 9: Surgical Treatment for Epilepsy -- Introduction -- Evaluation and Selection of the Surgical Candidate -- Resection Procedures -- Temporal Lobectomy -- Common Complications -- Extra-temporal Cortical Resections -- Hemispherectomy -- Nonresective Techniques -- Disconnection Surgeries -- Corpus Callosotomy -- Multiple Subpial Transections. Vagal Nerve Stimulation -- Deep Brain Stimulation -- Responsive Neurostimulation -- References -- Chapter 10: Clinical Evaluation of Epilepsy in the Brain-Tumor Patient -- Differential Diagnosis -- Clinical History and Physical Examination -- Neuroimaging Evaluation -- Clinical and Electrophysiological Work-Up -- Effects of Oncological Therapy on Brain Tumor-Related Epilepsy -- Acknowledgments -- References -- Chapter 11: Antiepileptic Drugs: -- Carbamazepine -- Ethosuximide -- Phenobarbital -- Phenytoin -- Primidone -- Alproate -- References -- Chapter 12: Antiepileptic Drugs: Second and Third Generation -- Introduction -- Clobazam -- Eslicarbazepine Acetate -- Ezogabine/Retigabine -- Felbamate -- Gabapentin -- Lacosamide -- Lamotrigine -- Levetiracetam -- Oxcarbazepine -- Perampanel -- Pregabalin -- Rufinamide -- Tiagabine Hydrochloride -- Topiramate -- Vigabatrin -- Zonisamide -- References -- Chapter 13: Antiepileptic Drugs and Brain Tumor Patients -- Introduction -- Pathophysiology -- Type of Seizure -- Treatment of Seizures -- First-Generation AEDs -- Newer AEDs -- Levetiracetam -- Oxcarbazepine -- Lacosamide -- Pregabalin -- Topiramate -- Zonisamide -- Lamotrigine -- Conclusion -- References -- Chapter 14: Clinical Approach to Brain Tumor-Related Epilepsy -- Seizure Prophylaxis in Patients with BTRE -- Is There a Best Practice for Seizure Treatment? -- Introduction -- Drug Resistance and Epileptogenicity -- Use of Systemic Treatment for Seizure Control -- Use of AEDs as Antineoplastic Treatment -- Efficacy of AEDs on BTRE: An Overview -- Adverse Events Specific to BTRE Patients -- Potential Interactions with Systemic Treatments -- Impact of AED Therapies on Cognition -- Impact of AED Therapies on QoL -- How to Choose an AED? -- Is It Possible to Stop an AED in BTRE, and When? -- Clinical Approach to BTRE -- Driving and BTRE -- References. Chapter 15: Neuropsychology of BTRE -- Introduction -- Overview of Neurocognitive Impairment in BT, Epilepsy, and BTRE -- Neurocognitive Impairment in BT -- Neurocognitive Impairment in Epilepsy -- Neurocognitive Impairment in BTRE -- Specific Cognitive Deficits in BT, Epilepsy, and BTRE -- Specific Cognitive Deficits in BT -- Specific Cognitive Deficits in Epilepsy -- Specific Cognitive Deficits in BTRE -- Overview of Neuropsychological Assessment Techniques for BT, Epilepsy, and BTRE -- Neuropsychological Assessment Techniques for BT -- Neuropsychological Assessment Techniques for Epilepsy -- Neuropsychological Assessment Techniques for BTRE -- Psychological Issues in BT, Epilepsy, and BTRE -- Psychological Issues in BT -- Psychological Issues in Epilepsy -- Psychological Issues in BTRE -- Sexual Disturbances in Patients with BT, Epilepsy and BTRE -- Sexual Disturbances in Patients with BT -- Sexual Disturbances in Patients with Epilepsy -- Sexual Disturbances in Patients with BTRE -- QoL Assessment and Monitoring in BT, Epilepsy and BTRE -- QoL Assessment and Monitoring in BT -- QoL Assessment and Monitoring in Epilepsy -- QoL Assessment and Monitoring in BTRE -- Conclusions -- References -- Chapter 16: Cognitive Rehabilitation in Patients with BTRE -- Introduction -- Goals of Cognitive Rehabilitation -- Treatment Modalities in BT -- Treatment Modalities in Epilepsy -- Treatment Modalities in BTRE -- Pharmacological Approaches for Treatment of Cognitive Deficits -- Caregivers Issues -- Implications for Future Research in BTRE -- References -- Chapter 17: Social Cost of Brain Tumor-Related Epilepsy -- Introduction -- Health Economic Reporting: Terminology and Aims -- Health Economics: Funding Priorities -- Health Technology Assessment -- BTRE: Economic Burden Within the Context of Neurological Disease -- Epilepsy -- Brain Tumor -- Conclusion. References -- Chapter Appendix: The Prospects of Brain Research within Horizon 2020: Responding Efficiently to Europe's Societal Needs ... -- Summary -- Index.
9780124171268
Epilepsy.
Electronic books.
RC372 -- .E655 2015eb
616.853
Epilepsy and Brain Tumors. - 1st ed. - 1 online resource (292 pages)
Front Cover -- Epilepsy and Brain Tumors -- Copyright -- Dedication -- Contents -- Foreword -- Preface -- Contributors -- Chapter 1: Brain Tumor-Related Epilepsy: Introduction and Overview -- Introduction -- Epilepsy: Definition, Incidence, Social Context and Treatment Options -- Epilepsy in the Context of BTs: Epidemiology and Incidence -- Detection, Classification, and Documentation of Seizures -- The Unique Role of Epileptogenesis and Drug Resistance in BTRE -- Pharmacoresistance -- QoL in BTRE Patients -- Impact of AEDs in BTRE Patients -- Neurocognitive Evaluation and Possible Rehabilitative Programs -- Health Economics and BTRE -- References -- Chapter 2: Overview of Epidemiology, Pathology, and Treatment of Primary Brain Tumors -- Epidemiology of PBT -- Pathology of Selected PBT -- Diffuse Astrocytomas -- Localized Astrocytomas -- Oligodendrogliomas and Oligoastrocytomas -- Medulloblastoma and Other Embryonal Tumors -- Meningioma and Other Tumors of the Meninges -- Primary Central Nervous System Lymphoma -- Surgical Therapy of PBT -- Radiation Therapy of PBT -- Chemotherapy of PBT -- Molecular or ``Targeted´´ Treatment -- References -- Chapter 3: Overview of Epidemiology, Pathology, and Treatment of Metastatic Brain Tumors -- Epidemiology of MBTs -- Pathology of MBTs -- Surgical Therapy of MBTs -- Radiation Therapy of MBTs -- Chemotherapy of MBTs -- Acknowledgments -- References -- Chapter 4: Supportive Care of Brain Tumor Patients -- Introduction -- Seizures and Anticonvulsant Therapy -- Corticosteroids -- Gastric Acid Inhibitors -- Thromboembolic Complications and Anticoagulation -- Dysphagia and Swallowing Disorders -- Psychiatric Issues -- Pain Control Issues -- Palliative Care -- Ethical Issues -- Conclusion -- References -- Chapter 5: Brain-Tumor-Related Epilepsy in Children -- The Pediatric Perspective. Epilepsy-Associated Brain Tumors -- Pathophysiology -- Epidemiology -- Brain Tumors -- Seizures and Epilepsy -- Presentation -- Brain Tumors -- Seizures and Epilepsy -- General Principles of Management -- History and Physical Exam -- Diagnostic Evaluation -- Scalp EEG -- Intracranial EEG -- MRI -- Other Imaging Studies -- Magnetic and Electrical Source Localization -- Neuropsychological Assessment and Other Studies Used to Localize Eloquent Brain -- Genetics -- Tissue Diagnosis and Molecular Tumor Markers -- Medical Management -- Anticipatory Guidance -- Maintenance Antiseizure Drugs -- Rescue Antiseizure Drugs -- Role of Antiseizure Drugs in Children Without a History of Seizures -- Chemotherapy, Biologic Agents, and Steroids -- Dietary Considerations and Alternative Therapies -- Surgical Management -- Goals and Approaches -- Timing of Surgical Resection -- Lesionectomy (Tumorectomy) Versus Lesionectomy ``Plus´´ -- Palliative Strategies -- Outcome -- Future Directions -- References -- Chapter 6: Mechanisms of Focal Epileptogenesis -- Time Course and Specificity of Acquired Epileptogenesis -- References -- Chapter 7: Pathophysiology of Brain Tumor-Related Epilepsy -- Introduction -- Epidemiology of BTRE -- Pathophysiology of BTRE -- Treatment of BTRE -- References -- Chapter 8: The Neurophysiology of Central Nervous System Tumors -- Introduction -- EEG Modalities and Applications -- EEG Background Changes -- Epileptiform Activity -- Meningiomas -- Generation of Abnormal Cerebral Activity -- References -- Chapter 9: Surgical Treatment for Epilepsy -- Introduction -- Evaluation and Selection of the Surgical Candidate -- Resection Procedures -- Temporal Lobectomy -- Common Complications -- Extra-temporal Cortical Resections -- Hemispherectomy -- Nonresective Techniques -- Disconnection Surgeries -- Corpus Callosotomy -- Multiple Subpial Transections. Vagal Nerve Stimulation -- Deep Brain Stimulation -- Responsive Neurostimulation -- References -- Chapter 10: Clinical Evaluation of Epilepsy in the Brain-Tumor Patient -- Differential Diagnosis -- Clinical History and Physical Examination -- Neuroimaging Evaluation -- Clinical and Electrophysiological Work-Up -- Effects of Oncological Therapy on Brain Tumor-Related Epilepsy -- Acknowledgments -- References -- Chapter 11: Antiepileptic Drugs: -- Carbamazepine -- Ethosuximide -- Phenobarbital -- Phenytoin -- Primidone -- Alproate -- References -- Chapter 12: Antiepileptic Drugs: Second and Third Generation -- Introduction -- Clobazam -- Eslicarbazepine Acetate -- Ezogabine/Retigabine -- Felbamate -- Gabapentin -- Lacosamide -- Lamotrigine -- Levetiracetam -- Oxcarbazepine -- Perampanel -- Pregabalin -- Rufinamide -- Tiagabine Hydrochloride -- Topiramate -- Vigabatrin -- Zonisamide -- References -- Chapter 13: Antiepileptic Drugs and Brain Tumor Patients -- Introduction -- Pathophysiology -- Type of Seizure -- Treatment of Seizures -- First-Generation AEDs -- Newer AEDs -- Levetiracetam -- Oxcarbazepine -- Lacosamide -- Pregabalin -- Topiramate -- Zonisamide -- Lamotrigine -- Conclusion -- References -- Chapter 14: Clinical Approach to Brain Tumor-Related Epilepsy -- Seizure Prophylaxis in Patients with BTRE -- Is There a Best Practice for Seizure Treatment? -- Introduction -- Drug Resistance and Epileptogenicity -- Use of Systemic Treatment for Seizure Control -- Use of AEDs as Antineoplastic Treatment -- Efficacy of AEDs on BTRE: An Overview -- Adverse Events Specific to BTRE Patients -- Potential Interactions with Systemic Treatments -- Impact of AED Therapies on Cognition -- Impact of AED Therapies on QoL -- How to Choose an AED? -- Is It Possible to Stop an AED in BTRE, and When? -- Clinical Approach to BTRE -- Driving and BTRE -- References. Chapter 15: Neuropsychology of BTRE -- Introduction -- Overview of Neurocognitive Impairment in BT, Epilepsy, and BTRE -- Neurocognitive Impairment in BT -- Neurocognitive Impairment in Epilepsy -- Neurocognitive Impairment in BTRE -- Specific Cognitive Deficits in BT, Epilepsy, and BTRE -- Specific Cognitive Deficits in BT -- Specific Cognitive Deficits in Epilepsy -- Specific Cognitive Deficits in BTRE -- Overview of Neuropsychological Assessment Techniques for BT, Epilepsy, and BTRE -- Neuropsychological Assessment Techniques for BT -- Neuropsychological Assessment Techniques for Epilepsy -- Neuropsychological Assessment Techniques for BTRE -- Psychological Issues in BT, Epilepsy, and BTRE -- Psychological Issues in BT -- Psychological Issues in Epilepsy -- Psychological Issues in BTRE -- Sexual Disturbances in Patients with BT, Epilepsy and BTRE -- Sexual Disturbances in Patients with BT -- Sexual Disturbances in Patients with Epilepsy -- Sexual Disturbances in Patients with BTRE -- QoL Assessment and Monitoring in BT, Epilepsy and BTRE -- QoL Assessment and Monitoring in BT -- QoL Assessment and Monitoring in Epilepsy -- QoL Assessment and Monitoring in BTRE -- Conclusions -- References -- Chapter 16: Cognitive Rehabilitation in Patients with BTRE -- Introduction -- Goals of Cognitive Rehabilitation -- Treatment Modalities in BT -- Treatment Modalities in Epilepsy -- Treatment Modalities in BTRE -- Pharmacological Approaches for Treatment of Cognitive Deficits -- Caregivers Issues -- Implications for Future Research in BTRE -- References -- Chapter 17: Social Cost of Brain Tumor-Related Epilepsy -- Introduction -- Health Economic Reporting: Terminology and Aims -- Health Economics: Funding Priorities -- Health Technology Assessment -- BTRE: Economic Burden Within the Context of Neurological Disease -- Epilepsy -- Brain Tumor -- Conclusion. References -- Chapter Appendix: The Prospects of Brain Research within Horizon 2020: Responding Efficiently to Europe's Societal Needs ... -- Summary -- Index.
9780124171268
Epilepsy.
Electronic books.
RC372 -- .E655 2015eb
616.853