Gene Action : A Historical Account.

Intro -- Contents -- I: The Classical Period, 1860-1940 -- 1 Overture: The Garden of Mendel -- 2 Building a Scaffold: Genes Within Chromosomes -- II: One Gene-One Enzyme, 1900-1953 -- 3 The Dawn of the One Gene-One Enzyme Hypothesis During the Classical Period -- 4 The Neurospora Era -- 5 Escherichia coli Enters the Field -- 6 Biochemical Genetics in Escherichia coli -- 7 The Chemical Nature of Genes -- III: How Genes Determine Protein Structure, 1953-1965 -- 8 Building a Theoretical Framework for Gene Action -- 9 Biochemical Identification of Adaptors -- 10 The Elusive Messenger -- 11 Deciphering the Code -- IV: Regulation or Gene Action -- 12 Feedback Control of Biosynthetic Pathways -- 13 Adaptive Enzymes -- 14 The Operon Model -- V: In the Aftermath of the Operon Model, 1965-2000 -- 15 The Floodgates Open -- Appendix: Further Readings and Comments -- Index -- A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- R -- S -- T -- U -- V -- W -- X -- Y -- Z.

This is the only book written by someone working in the field that deals with the history of gene action. It focuses on the spectacular developments that occurred between 1940 and 1965 in understanding the biochemical nature and action of genes. The author experienced these developments firsthand and is thus able to give an insider's account of an extraordinary period in the history of biology. The last part of the book describes the advances made since 1965 that have put genes in the central position they occupy today.

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Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2024. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.